Alzheimer's Disease: Reducing the burden with ApoE2

The Effect of Resilience Training on Reducing the Care Burden of Families with Schizophrenic Patients

Introduction: Schizophrenia is the most severe chronic psychiatric disorder that associated with impaired social and occupational abilities. In addition to the patient this disorder also affects the entire family system. The care burden is the psychological, physical and social stress that comes to caregivers as a result of long-term care. Therefore it causes many problems such as burnout, anxi...

Magnesium and Alzheimers Disease: The Cholinergic Hypothesis

The cholinergic deficit in Alzheimer’s disease (AD) remains the cornerstone for the understanding of chemical signal transfer. Hypofunctions of cholinergic systems are significantly involved in the signs and symptoms of senile dementia of the Alzheimer type. Cognitive deficits in AD have been widely associated with dysfunction of the cholinergic system. As a diagnostic marker of AD the activity...

Reducing the burden of inherited disease: the Human Variome Project.

Reducing the Global Burden of Cardiovascular Disease, Part 1

The epidemiological transition in the 20th century was accompanied by a fall in deaths and disability from communicable diseases and an increase in noncommunicable diseases (NCDs). Of the NCDs, cardiovascular disease (CVD) is now the leading cause of mortality and morbidity worldwide. In 2013, the World Health Organization launched the 25×25 Global Action Plan, an ambitious road map for countri...

Initiatives in Medical Volunteerism Aimed at Reducing the Burden of Orthopedic Disease in Low- and Middle-Income Countries

While infectious disease garners much attention and research funding globally, initiatives aimed at treating traumatic orthopedic injuries are underfunded despite such injuries accounting for a significant degree of morbidity worldwide. In recent years, a number of organizations have sought to alleviate this burden through treatment and educational initiatives in low- and middle-income countrie...